Optimizing dentin bond durability: Control of collagen degradation by matrix metalloproteinases and cysteine cathepsins
نویسندگان
چکیده
منابع مشابه
Effect of different synthetic matrix metalloproteinase inhibitors on composite-dentin microtensile bond strength durability
Background and Aims: Despite patient’s demand increased for tooth color restorations, the stable bond between dentin and composite is a challenge in dentistry. Dentin protease activation is responsible for dentin-resin bond failure. The aim of this study was to determine the best pretreatment agent to inhibit matrix metalloproteinase and increase resin-dentin bond durability. Materials and Met...
متن کاملThe effects of host derived metalloproteinases on dentin bond and the role of MMPs inhibitors on dentin matrix degradation.
OBJECTIVES The work has the objective to analyze the literature on the degradation of the adhesive interface. In particular the study is focused on the role of the metalloproteinase in the hydrolytic degradation of collagen matrix in the bonded interface. The survey will concern also the latest innovations to improve and increase the link between dentin and the restorative materials through the...
متن کاملBleaching agents increase metalloproteinases-mediated collagen degradation in dentin.
INTRODUCTION Tooth bleaching is based on hydrogen peroxide application. The Objective of this study was to determine whether dental bleaching agents affect metalloproteinases-mediated dentin collagen degradation. METHODS Human dentin specimens were subjected to different treatments: (1) untreated dentin; (2) demineralization by 37% phosphoric acid (PA); (3) demineralization by 37% PA, followe...
متن کاملDentin matrix degradation by host matrix metalloproteinases: inhibition and clinical perspectives toward regeneration
Bacterial enzymes have long been considered solely accountable for the degradation of the dentin matrix during the carious process. However, the emerging literature suggests that host-derived enzymes, and in particular the matrix metalloproteinases (MMPs) contained in dentin and saliva can play a major role in this process by their ability to degrade the dentin matrix from within. These finding...
متن کاملBond durability of contemporary adhesive systems to pulp chamber dentin
Objective: The purpose of this study was to evaluate long-term bond strengths of dentin adhesive systems, which include one-step self-etch adhesive systems (Optibond All-in-one, Kerr; Adper Prompt L-POP, 3 M ESPE), a three-step etch-and-rinse adhesive (Optibond FL, Kerr) and two-step self-etch adhesive (AdheSE Bond, Ivoclar), applied to pulp chamber dentin surfaces after 12-month water storage ...
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ژورنال
عنوان ژورنال: Dental Materials
سال: 2013
ISSN: 0109-5641
DOI: 10.1016/j.dental.2012.08.004